This website is for UK Healthcare Professionals

Electronic Pregnancy Prevention Programme portal (ePPP) now available for thalidomide, lenalidomide and pomalidomide

Visit the Portal (ePPP) page to learn more and request a demonstration

Therapeutic Indications1,4,6

Thalidomide

Thalidomide capsules in combination with melphalan and prednisone is indicated as first line treatment of patients with untreated multiple myeloma, aged ≥ 65 years or ineligible for high dose chemotherapy.

Thalidomide capsules are prescribed and dispensed according to the Thalidomide Pregnancy Prevention Programme (see section 4.4 of the SmPC)

Lenalidomide Accord

Multiple myeloma​​​​​

Lenalidomide Accord as monotherapy is indicated for the maintenance treatment of adult patients with newly diagnosed multiple myeloma who have undergone autologous stem cell transplantation.

Lenalidomide Accord as combination therapy with dexamethasone, or bortezomib and dexamethasone, or melphalan and prednisone (see section 4.2 of the SmPC) is indicated for the treatment of adult patients with previously untreated multiple myeloma who are not eligible for transplant.

Lenalidomide Accord in combination with dexamethasone is indicated for the treatment of multiple myeloma in adult patients who have received at least one prior therapy. 

Myelodysplastic syndromes​​​​​

Lenalidomide Accord as monotherapy is indicated for the treatment of adult patients with transfusion-dependent anaemia due to low- or intermediate-1-risk myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality when other therapeutic options are insufficient or inadequate.

Mantle cell lymphoma​​​​​

Lenalidomide Accord as monotherapy is indicated for the treatment of adult patients with relapsed or refractory mantle cell lymphoma (see sections 4.4 and 5.1 of the SmPC)

Follicular lymphoma​​​​​

Lenalidomide Accord in combination with rituximab (anti-CD20 antibody) is indicated for the treatment of adult patients with previously treated follicular lymphoma (Grade 1 – 3a).

Pomalidomide

Pomalidomide in combination with bortezomib and dexamethasone is indicated in the treatment of adult patients with multiple myeloma who have received at least one prior treatment regimen including lenalidomide.

Pomalidomide in combination with dexamethasone is indicated in the treatment of adult patients with relapsed and refractory multiple myeloma who have received at least two prior treatment regimens, including both lenalidomide and bortezomib, and have demonstrated disease progression on the last therapy.

The Pregnancy Prevention Programme (PPP) process

Please refer to the SmPC and the Accord thalidomide/lenalidomide/pomalidomide Healthcare Professional Brochure before prescribing

Details on how to return the paper PRF and PAF to Accord can be found on each form
Details on how to return the paper PRF and PAF to Accord can be found on each form

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Accord-UK Ltd on 01271 385257 or email [email protected].

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For UK Healthcare Professionals

If you are a UK healthcare professional and would like more information on thalidomide, lenalidomide or pomalidomide from Accord, please click here

Report Adverse Events

Adverse events should be reported.
Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in Google Play or Apple App Store.

Adverse events should also be reported to Accord-UK Ltd:

For the UK Public

For more information on thalidomide, lenalidomide or pomalidomide from Accord, please click below

Site intended for a UK audience only. UK-03777 June 2025